Pass Pharmacy Tech

Free PTCB practice questions

33 original questions from the free modules. Choose an answer before opening the explanation. These are study questions, not official PTCB exam items.

1. Atorvastatin (Lipitor) belongs to which drug class?

Answer and explanation

HMG-CoA reductase inhibitor (statin)

Atorvastatin is a statin — it inhibits HMG-CoA reductase to lower LDL cholesterol production.

2. Metoprolol is best classified as which class?

Answer and explanation

Beta blocker

The '-olol' suffix identifies beta blockers. Metoprolol is a cardioselective beta-1 blocker.

3. Famotidine is classified as a:

Answer and explanation

H2 blocker

The '-tidine' suffix identifies H2 receptor blockers. Famotidine is OTC for heartburn.

4. Alprazolam (Xanax) belongs to which class?

Answer and explanation

Benzodiazepine

Alprazolam is a benzodiazepine (Schedule IV). Suffixes '-azepam' and '-azolam' identify the class.

5. What is the generic name for Lipitor?

Answer and explanation

Atorvastatin

Lipitor is the brand name for atorvastatin.

6. What is the brand name for sildenafil?

Answer and explanation

Viagra

Sildenafil is sold as Viagra (erectile dysfunction) and Revatio (pulmonary hypertension).

7. Generic for Glucophage:

Answer and explanation

Metformin

Glucophage is a brand name for metformin, a biguanide used to improve glycemic control in type 2 diabetes.

8. Generic for Singulair:

Answer and explanation

Montelukast

Singulair is brand-name montelukast, a leukotriene receptor antagonist for asthma and allergic rhinitis.

9. Albuterol is most commonly indicated for:

Answer and explanation

Acute bronchospasm in asthma/COPD

Albuterol is a short-acting beta-2 agonist used as a rescue bronchodilator.

10. Common use of warfarin:

Answer and explanation

Anticoagulation

Warfarin is an oral vitamin K antagonist anticoagulant used for AFib, DVT/PE, and mechanical valves.

11. What is the generic name for Zoloft?

Answer and explanation

Sertraline

Zoloft is the brand name for sertraline, an SSRI for depression and anxiety disorders.

12. Apixaban is the generic name for which brand?

Answer and explanation

Eliquis

Apixaban is Eliquis, a direct oral anticoagulant (factor Xa inhibitor); rivaroxaban is Xarelto.

13. Ondansetron (Zofran) is dispensed to:

Answer and explanation

Prevent nausea and vomiting

Ondansetron is a 5-HT3 receptor antagonist used to prevent nausea and vomiting associated with specified chemotherapy, radiotherapy, or surgery.

14. A patient reports a severe penicillin allergy. Which antibiotic on the shelf is a documented cross-reaction risk to flag for the pharmacist?

Answer and explanation

Cephalexin (Keflex)

Cephalexin is a cephalosporin beta-lactam; its label warns about cross-hypersensitivity with penicillins. The technician flags the allergy for pharmacist assessment rather than selecting an alternative antibiotic.

15. The counseling flag that MUST accompany metronidazole (Flagyl):

Answer and explanation

Avoid alcohol and propylene glycol during therapy and for at least three days afterward

The Flagyl label warns that alcohol or propylene glycol may cause abdominal cramps, nausea, vomiting, headache, and flushing. Avoid them during treatment and for at least three days after the last dose.

16. Lantus is the brand name for:

Answer and explanation

Insulin glargine

Lantus is insulin glargine, a long-acting basal insulin; lispro (Humalog) and aspart (Novolog) are rapid-acting, detemir is Levemir.

17. Which drug requires routine INR blood-test monitoring?

Answer and explanation

Warfarin (Coumadin)

Warfarin's effect on vitamin K-dependent clotting factors is measured by the INR; DOACs like apixaban were designed to avoid routine INR monitoring.

18. Semaglutide (Ozempic) belongs to which drug class?

Answer and explanation

GLP-1 receptor agonist

Semaglutide is a GLP-1 receptor agonist. Ozempic injection is dosed once weekly; the drug class also includes oral formulations, so injectable is not a class-wide requirement.

19. Hydrochlorothiazide is most commonly prescribed for:

Answer and explanation

Hypertension and edema

Hydrochlorothiazide is a thiazide diuretic labeled for hypertension and selected causes of edema.

20. Indication for ipratropium (Atrovent):

Answer and explanation

COPD maintenance bronchodilation

Ipratropium is a short-acting anticholinergic bronchodilator commonly used for COPD; often combined with albuterol.

21. A characteristic adverse effect of ACE inhibitors is:

Answer and explanation

Dry persistent cough

Persistent nonproductive cough is a recognized ACE-inhibitor adverse effect, plausibly related to reduced bradykinin breakdown. Refer the concern to the pharmacist and prescriber; a technician does not independently change therapy.

22. Common adverse effect of metformin:

Answer and explanation

GI upset / diarrhea, rarely lactic acidosis

Diarrhea and other gastrointestinal effects are common with metformin. Its boxed warning concerns lactic acidosis. It is contraindicated with eGFR below 30 mL/min/1.73 m²; temporary interruption for iodinated contrast depends on the label criteria and clinical assessment.

23. Spironolactone may cause:

Answer and explanation

Hyperkalemia and gynecomastia

Spironolactone is a potassium-sparing diuretic that also blocks androgen receptors → hyperkalemia and gynecomastia.

24. Long-term PPI use has been associated with:

Answer and explanation

B12 deficiency, hypomagnesemia, fracture risk

PPI labels warn about B12 deficiency with prolonged use, hypomagnesemia, fracture risk, and Clostridioides difficile-associated diarrhea. These risks require appropriate clinical assessment.

25. Grapefruit juice can dangerously increase levels of:

Answer and explanation

Simvastatin

Grapefruit inhibits CYP3A4 in the gut wall; simvastatin/atorvastatin/lovastatin levels rise, raising rhabdomyolysis risk.

26. Tetracycline absorption can be reduced by taking it together with:

Answer and explanation

Calcium, iron, or antacids (chelation)

Antacids containing aluminum, calcium, or magnesium and iron-containing preparations can impair tetracycline absorption. Follow the specific product label and pharmacist instructions for separation; one universal two-hour interval does not fit every antibiotic.

27. MAOIs taken with foods containing tyramine cause:

Answer and explanation

Hypertensive crisis

MAOIs prevent tyramine breakdown; aged cheese, cured meats, wine → severe hypertension.

28. The ending “-prazole” is a common memory cue for which drug class, as in omeprazole and pantoprazole?

Answer and explanation

Proton pump inhibitors

Omeprazole and pantoprazole are proton pump inhibitors. Name endings are memory cues, not a substitute for checking the complete drug name; exceptions exist.

29. Ciprofloxacin's "-floxacin" stem places it in which antibiotic class?

Answer and explanation

Fluoroquinolones

The -floxacin stem identifies fluoroquinolones (ciprofloxacin, levofloxacin, moxifloxacin) — the class with tendon-rupture warnings and cation-binding interactions.

30. Nystatin is classified as:

Answer and explanation

An antifungal

Nystatin is a topical/oral antifungal (thrush, candidal skin infections). Despite the name, it is unrelated to cholesterol statins.

31. Sumatriptan's "-triptan" stem identifies it as a drug for:

Answer and explanation

Acute migraine

The -triptan stem marks selective serotonin 5-HT1 agonists (sumatriptan, rizatriptan) used to abort acute migraine attacks.

32. Enoxaparin's "-parin" stem places it in which drug family?

Answer and explanation

Heparin-type anticoagulants

The -parin stem marks the heparin family; enoxaparin (Lovenox) is a low-molecular-weight heparin given by subcutaneous injection.

33. Which minocycline safety information should a technician flag for pharmacist counseling?

Answer and explanation

Photosensitivity and interactions with antacids or iron

Minocycline is a tetracycline antibiotic. Its label reports photosensitivity and impaired absorption with aluminum-, calcium-, or magnesium-containing antacids and iron. Food and dairy instructions are formulation-specific; the referenced immediate-release capsule may be taken with or without food.